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Bulk Supply high-purity Phosphatidylserine
Time：2026-10-221. Definition
Bulk Supply Phosphatidylserine is a high-purity soy-derived phospholipid compound offered as a white to off-white powder, designed for dietary supplement manufacturers and food & beverage brands that require a reliable, consistently standardized cognitive health ingredient for large-scale production.
2. Core Selling Points
≥50% Phosphatidylserine Content by HPLC: Each batch delivers verified potency by high-performance liquid chromatography (HPLC), eliminating dosage uncertainty in finished products and enabling precise label claims.≥98% Total Phospholipids: The purified composition ensures better emulsification and absorption in finished formulations compared to lower-grade extracts, yielding a more bioavailable final product.
Heavy Metal Compliance (Pb ≤ 0.5 mg/kg, As ≤ 0.5 mg/kg): Exceeds the European Pharmacopoeia (EP) heavy metal standards for dietary ingredients, providing a clean safety profile suitable for global regulatory submissions.
20 kg (44.09 lb) Fiber Drums, Customizable Packaging: Packaging options include 20 kg fiber drums with two PE liners, as well as customized 25 kg, 50 kg, or 100 kg packaging upon request, accommodating diverse production scales from pilot batches to full industrial runs.
Cold Chain Not Required, 24-Month Shelf Life: The powder formulation remains stable for 24 months without cold chain logistics, simplifying global shipping and reducing storage overhead. This stability is verified by accelerated stability studies conducted according to ICH guidelines.
3. Detailed Specifications
| Parameter | Value | Additional Information |
|---|---|---|
| Product Name | Phosphatidylserine (PS) | Bulk powder form |
| CAS Number | 514-46-5 | Reference standard |
| Molecular Formula | C42H82NO8P | Identified via mass spectrometry |
| Molecular Weight | 763.03 g/mol | Theoretical value |
| Appearance | White to off-white powder | Free-flowing, no visible impurities |
| Assay (PS by HPLC) | ≥ 50% | Test method: HPLC-ELSD, verified per batch |
| Total Phospholipids | ≥ 98% | Includes PS, PC, PE, PI |
| Loss on Drying | ≤ 3.0% | Measured by 105°C for 3 hours |
| Heavy Metals | Pb ≤ 0.5 mg/kg; As ≤ 0.5 mg/kg | Test method: ICP-MS, meets EP limits |
| Microbial Total Plate Count | ≤ 1000 CFU/g | Meets USP<2021>microbial limits |
| Salmonella | Negative / 25 g | Test method: USP<2022> |
| E. coli | Negative / 10 g | Test method: USP<2022> |
| Solvent Residues | Ethanol ≤ 5000 mg/kg | Meets ICH Q3C Class 3 limits |
| Particle Size | ≥ 95% through 80 mesh | Standard sieve analysis |
| Main Source | Non-GMO soy lecithin | Enzymatic conversion process (PLP-dependent phospholipase D) |
| Batch Size | 500 kg standard; 1000 kg upon request | Full batch traceability with COA |
| Country of Origin | China | HACCP and ISO 9001 certified facility |
| Shelf Life | 24 months | Under sealed, dry, cool conditions (< 25°C) |
| Recommended Storage | Sealed container, dry, < 25°C | Protect from sunlight; no refrigeration needed |
4. Application Scenarios
Cognitive Health Supplement Production: A nutraceutical manufacturer formulates PS into softgels or capsules for memory support products targeting adults aged 50+, using the 50% standardized PS content to ensure dose accuracy at 100 mg per serving.
Sports Nutrition Product Development: An active lifestyle brand incorporates PS into pre-workout powders to support exercise-induced cortisol management, relying on the ≥98% phospholipid purity for rapid dispersion in liquid formulations.
Functional Food & Beverage Fortification: A food company fortifies a ready-to-drink breakfast shake with PS in powder form, benefiting from the neutral taste and emulsion-friendly profile of the ingredient.
Pediatric ADHD Support Formulation: A medical nutrition company develops chewable tablets for children with attention difficulties, using the consistently low heavy metal profile to meet stringent pediatric regulatory standards in EU markets.
Private Label Product Launch: A fast-growing e-commerce brand creates a nootropic gummy line with PS as a key ingredient, depending on the supplier's 500 kg standard batch size to ensure supply chain consistency across multiple Season launches.
5. Frequently Asked Questions
What is phosphatidylserine bulk powder mainly used for?
In the dietary supplement industry, bulk PS powder is primarily used as the active ingredient in formulations targeting memory improvement, cognitive support in aging populations, and stress-related cortisol management, at typical doses of 100–300 mg/day.
How much phosphatidylserine should I use in a daily supplement formulation?
For cognitive support products, a 100 mg per serving dosage is supported by clinical research; for stress relief claims, 400 mg/day has been studied in clinical trials. Confirm target doses with your regulatory consultant.
What is the difference between sunflower and soy-derived phosphatidylserine in bulk?
Soy-derived PS is the most extensively studied form in clinical literature and costs less than sunflower-derived alternatives; sunflower PS is chosen mainly for allergen-free label claims. This product is soy-derived.
Can this bulk phosphatidylserine be used in gummies or chewable tablets?
Yes, the powder's 80-mesh particle fineness and neutral flavor profile allow incorporation into chewable tablets and gummy bases, but you must verify heat stability under your specific processing conditions above 60°C.
What are the main quality certifications for this product?
The production facility holds ISO 9001 and HACCP certifications, and each batch is tested for HPLC assay, heavy metals, and microbial limits with a Certificate of Analysis. Kosher and Halal certifications are available upon request.
How stable is the phosphatidylserine powder during shipping in summer?
The powder requires no cold chain and remains stable at temperatures below 25°C. For summer shipping, standard insulated packaging is recommended to avoid prolonged exposure to temperatures above 40°C during transit.
What is the recommended minimum order quantity for the first trial?
A standard trial order is 25 kg in one fiber drum, and production-scale orders range from 500 kg to 1000 kg per batch. For large-volume contracts, sample retention and stability data are provided at no charge.
Do you provide third-party testing results or certificates for the batch we purchase?
Yes, each batch is accompanied by a full Certificate of Analysis, and third-party testing (e.g., Eurofins or SGS) can be arranged at an additional cost if you request it during the purchase agreement phase.
6. Differentiation Summary
Compared to typical bulk suppliers that offer inconsistent 20–40% PS content with ambiguous quality documentation, this product supplies a verified 50% HPLC-validated active content with full traceability from non-GMO soy lecithin feedstock through enzymatic conversion, paired with complete heavy metal, microbial, and solvent residue data per batch. It is specifically positioned for mid-to-large scale manufacturers and brands that need reproducible clinical-level quality, compliance-ready documentation, and flexible industrial packaging, without paying the premium margins charged by Western brokers reselling the same Chinese-sourced material. For formulators who prioritize batch-to-batch consistency, verifiable purity, and direct-supplier efficiency, this bulk PS powder provides the most reliable cost-performance balance on the market.
