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The protective effect of phospholipids on cardiovascular health

Time:2025-07-11

Phospholipids exert significant protective effects on cardiovascular health, with their mechanisms primarily involving regulating blood lipids, protecting vascular endothelium, and inhibiting thrombosis, supported by relevant clinical evidence. Details are as follows:

Protective Mechanisms:

Regulating blood lipids: Phosphatidylcholine in phospholipids has an emulsifying effect, which can emulsify cholesterol and triglycerides in the blood into tiny particles, making them easier to be transported and metabolized, thereby preventing lipid deposition on blood vessel walls. Meanwhile, it can promote the decomposition of low-density lipoprotein (LDL), reduce serum total cholesterol and LDL cholesterol levels, and increase high-density lipoprotein (HDL) cholesterol levels, helping to maintain lipid balance.

Protecting vascular endothelium: Phospholipids can repair damaged vascular endothelial cell membranes, enhance the flexibility and fluidity of cell membranes, make blood vessel walls smoother, reduce damage to vascular endothelium caused by harmful substances in the blood, and thus lower the risk of atherosclerosis.

Inhibiting thrombosis: By reducing blood viscosity and improving serum lipids, phospholipids decrease platelet deposition on blood vessel walls, thereby reducing the likelihood of thrombosis and helping to prevent thrombotic diseases such as myocardial infarction and stroke.

Alleviating inflammatory responses: Phospholipids can inhibit inflammatory responses in blood vessel walls, reduce the release of inflammatory factors, prevent the occurrence and progression of arteriosclerosis, and thus protect the cardiovascular system.

Clinical Evidence:

Relevant clinical studies have shown that daily intake of 1.2-2.4g of phospholipids can reduce LDL by 15%-20% and serum total cholesterol by 15%-25%, demonstrating its favorable effect in regulating blood lipids. This is of positive significance for people with hyperlipidemia and can effectively reduce the risk of cardiovascular diseases.