High purity Phosphatidylserine 51446-62-9
Time:2026-10-27High purity phosphatidylserine is a naturally occurring phospholipid supplement, primarily intended for adults seeking cognitive support, designed to address age-related memory decline, occasional forgetfulness, and difficulty concentrating.
Core Benefits
Purity level of 95% or higher ensures a potent dose of active phosphatidylserine per serving, requiring fewer softgels to achieve an effective daily intake of 100 mg to 300 mgHPLC-verified concentration guarantees batch-to-batch consistency, so each capsule delivers the exact labeled amount without variance between lots
Solvent-free extraction process eliminates residual hexane or ethanol contamination risks, making the product suitable for long-term daily supplementation
Clinically studied dosage range of 300 mg/day aligns with research protocols used in cognitive aging studies, allowing users to match outcomes reported in published trials
Non-GMO soybean-derived source provides a plant-based alternative to bovine brain extracts, reducing concerns related to animal-sourced supplements
Technical Specifications
| Parameter | Value | Additional Information |
|---|---|---|
| Purity (HPLC) | ≥ 95% | Third-party lab tested |
| Phosphatidylserine content per serving | 300 mg (3 softgels) | 100 mg per softgel |
| Form | Softgel capsules | For enhanced absorption |
| Softgel count | 60 or 120 capsules per bottle | Equivalent to 20 or 40 days of use |
| Source | Non-GMO soy lecithin | Enzymatically converted |
| Residual solvents | Not detected | GC-MS analysis per USP 467 |
| Heavy metals | ≤ 1 ppm lead, ≤ 0.5 ppm arsenic | ICP-MS testing |
| Shelf life | 24 months from manufacturing date | Store in a cool, dry place |
| Allergen information | Contains soy | Free from gluten, dairy, and eggs |
| Manufacture standard | cGMP certified facility | FDA-registered production site |
| Storage condition | 15–25°C (59–77°F) | Avoid direct sunlight |
Applicable Scenarios
Adults over 45 experiencing mild memory lapses take 300 mg daily to support recall speed and short-term memory retention, based on a 6-month double-blind trial published in the Journal of Clinical Biochemistry and NutritionWorking professionals under high cognitive load use phosphatidylserine to maintain focus during extended mental work sessions, with one study on 42 individuals reporting improved attention scores after 6 weeks
Students during exam preparation periods add 100 mg to 200 mg before study sessions to support concentration and working memory capacity, as demonstrated in a 2017 crossover study involving university students
Athletes and high-intensity exercisers supplement with phosphatidylserine to manage exercise-induced cortisol spikes and reduce perceived soreness, based on research from the International Journal of Sports Nutrition
Older adults seeking long-term cognitive maintenance incorporate 300 mg daily as part of their routine, aligning with a 12-week randomized trial that observed improved logical memory performance compared to placebo
Frequently Asked Questions
How long does phosphatidylserine take to show noticeable effects?Most clinical trials report measurable cognitive improvements after 6 to 12 weeks of continuous use at 300 mg daily.
Can I take phosphatidylserine with my regular multivitamin?Yes, no known negative interactions exist between phosphatidylserine and common vitamin or mineral supplements.
Is high purity phosphatidylserine safe for daily long-term use?Clinical trials lasting up to 6 months report no serious adverse events, with mild stomach upset being the only occasionally reported side effect.
What is the difference between 95% purity and standard 20% powder?To receive 300 mg of active phosphatidylserine, 1.5 g of 20% powder is required versus just 316 mg of 95% powder, making high purity the more efficient choice.
Does this supplement require refrigeration to remain stable?No, storage at 15–25°C is sufficient; only liquid lecithin products require refrigeration.
What time of day should I take phosphatidylserine?Studies typically administer it in divided doses at breakfast and lunchtime to maintain steady blood levels throughout the day.
Can adults below 30 take phosphatidylserine to boost memory?Available evidence focuses on adults with cognitive complaints or age-related decline; benefits for young healthy adults without cognitive issues remain unproven.
Is this product safe for someone taking blood-thinning medication?Phosphatidylserine has no documented interaction with warfarin, but consult a physician before combining with any anticoagulant therapy.
What Makes It Different
Phosphatidylserine is abundant in retail supplements, but the majority of commercial products contain only 20% to 50% active ingredient, with the remainder composed of inert carrier lipids. This high purity formulation reverses that ratio, delivering 95% active phosphatidylserine per softgel. This concentration matters because it converts a 300 mg dose into a small, manageable capsule count rather than requiring 5 to 10 large softgels per day. The consequence is lower filler intake, reduced capsule burden, and a straightforward path to matching clinically validated doses. This product is best suited for individuals who have already tried conventional phosphatidylserine without noticeable results and are ready to examine whether purity percentage was the limiting factor in their experience.

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